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Advances in Materials Research
  Volume 9, Number 2, June 2020, pages 109-114
DOI: http://dx.doi.org/10.12989/amr.2020.9.2.109
 


Active components delivery rate from acrylic resin maxillary surgical obturator: Part I
Arshad Al-Kaabi and Mohammed A. Hamid

 
Abstract
    The purpose of this study was to observe the trend of compounds release from acrylic resin oral prosthesis when used for drug delivery as well as a restoration. In this study, 10 specimens of heat-cured polymethylmethacrylate material were prepared and loaded with methylene blue biological stain. The specimens were then submerged in vials with 5 ml distilled water for 24 hours. The extraction procedure continued for 4 days, each day the specimens were immersed in another 5 ml distilled water vial. All extracted solutions were analyzed by visible light spectroscopy for absorbance comparison. The statistical results showed that the absorbance values were significantly different in the first day of extraction than the following days. However, there was no statistical difference among the 2nd, 3rd and 4th days of extraction. Biological stain loading to acrylic resin at the mixing stage, and then after extraction in distilled water, showed a burst release during the first day followed by a constant release during the following few days.
 
Key Words
    acrylic resin; drug delivery; maxillary obturator; methylene blue
 
Address
Department of Dental Technology, College of Health and Medical Technology, Middle Technical University, Baghdad 00964, Iraq.
 

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