Interaction and Multiscale Mechanics Volume 4, Number 2, June 2011 , pages 165-171 DOI: https://doi.org/10.12989/imm.2011.4.2.165 |
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Development of a three-dimensional dynamic model for chemotaxis |
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Jihwan Song and Dongchoul Kim
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Abstract | ||
In this study, we proposed a three-dimensional dynamic model under the diffuse interface description for the single crawling cell. From the developed model, we described the clear evolution processes for crawling neutrophil and assessed the reliable quantitative chemotactic property, which confirmed the high possibility of adequate predictions. To establish the system considering of multiple mechanisms such as, diffusion, chemotaxis, and interaction with surface, a diffuse interface model is employed. | ||
Key Words | ||
chemotaxis; crawling cell; interface energy; cell migration; diffuse interface model. | ||
Address | ||
Jihwan Song and Dongchoul Kim: Department of Mechanical Engineering, Sogang University, 1 Shinsoo-dong, Mapo-go, Seoul, Republic of Korea | ||