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Interaction and Multiscale Mechanics
  Volume 4, Number 2, June 2011, pages 165-171
DOI: http://dx.doi.org/10.12989/imm.2011.4.2.165
 
open access

Development of a three-dimensional dynamic model for chemotaxis
Jihwan Song and Dongchoul Kim

 
Abstract
    In this study, we proposed a three-dimensional dynamic model under the diffuse interface description for the single crawling cell. From the developed model, we described the clear evolution processes for crawling neutrophil and assessed the reliable quantitative chemotactic property, which confirmed the high possibility of adequate predictions. To establish the system considering of multiple mechanisms such as, diffusion, chemotaxis, and interaction with surface, a diffuse interface model is employed.
 
Key Words
    chemotaxis; crawling cell; interface energy; cell migration; diffuse interface model.
 
Address
Jihwan Song and Dongchoul Kim: Department of Mechanical Engineering, Sogang University, 1 Shinsoo-dong, Mapo-go, Seoul, Republic of Korea
 

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