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Advances in Nano Research Volume 9, Number 2, August 2020 , pages 113-122 DOI: https://doi.org/10.12989/anr.2020.9.2.113 |
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Copper micro/nanostructures as effective SERS active substrates for pathogen detection |
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Balaprasad Ankamwar and Ujjal Kumar Sur
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| Abstract | ||
| Surface-Enhanced Raman Scattering (SERS) spectroscopy is a multifaceted surface sensitive methodology which exploits spectroscopy-based analysis for various applications. This technique is based on the massive amplification of Raman signals which were feeble previously in order to use them for appropriate identification at qualitative and quantitative in chemical as well as biological systems. This novel powerful technique can be utilized to identify pathogens such as bacteria and viruses. As far as SERS is concerned, one of the most studied problems has been functionalization of SERS active substrate. Metal colloids and nanostructures or microstructures synthesized using noble metals such as Au, Ag and Cu are considered to be SERS active. Silver and gold are extensively used as SERS active substrates due to chemical inertness and stability in air compare to copper. However, use of Cu as a suitable alternative has been taken into account as it is cheap. Herein, we have synthesized air-stable copper microstructures/nanostructures by chemical, electrochemical and microwave-assisted methods. In this paper, we have also discussed the use of as synthesized copper micro/nanostructures as inexpensive yet effective SERS active substrates for the fast identification of micro-organisms like Staphylococcus aureus and Escherichia coli. | ||
| Key Words | ||
| bacteria; surface-enhanced Raman scattering; copper microstructures/nanostructures (micro/nanostructures); Staphylococcus aureus; Escherichia coli; SERS active substrates | ||
| Address | ||
| (1) Balaprasad Ankamwar and Ujjal Kumar Sur: Bio-Inspired Materials Research Laboratory, Department of Chemistry, S.P. Pune University, Ganeshkhind, Pune-411007, India | ||