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Advances in Environmental Research
  Volume 1, Number 2, June 2012, pages 109-123
open access

Effects of solanum macrocarpon (African eggplant) on haematological parameters of wistar rats exposed to urban air pollution
A.A. Olajire and L. Azeez

    Our study investigated the effects of Solanum macrocarpon (African eggplant) on haematological and biochemical parameters of male albino rats exposed to urban air pollution (O3, PM10, CO, SO2, NO2 and VOC). Male albino Wistar rats were exposed for 63 days either to urban air pollution without treatment (A); oral supplementation with Solanum macrocarpon given at 36 and 75 mg/kg body weight (BW), representing C and D respectively and exposed to air pollution; oral supplementation with Solanum macrocarpon given at 75 mg/kg BW after exposure to air pollution (B); or kept in animal house without exposure to air pollution (E). Animals exposed to air pollution showed significant alterations in haematological and biochemical parameters signaling that the blood and organs were badly injured. There were significant elevations in white blood cells (WBC) and its indices, reduction in red blood cells (RBC) and significant depletions of non-enzymic antioxidants, total protein and increase in lipid peroxidation values. Solanum macrocarpon supplementation in the feed of animals halted significantly the deleterious effects of air pollution, with co-administration during exposure given better results.
Key Words
    Solanum macrocarpon; urban air pollution; haematological indices; biochemical indices; wistar rat
A.A. Olajire: Industrial and Environmental Chemistry Unit, Department of Pure and Applied Chemistry, Ladoke Akintola University of Technology, Ogbomoso, Nigeria; L. Azeez: Department of Chemical Sciences, Fountain University, Osogbo, Nigeria

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