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Advances in Biomechanics & Applications
  Volume 1, Number 4, December 2014, pages 279-292
open access

Coronary three vessel disease: hydrodynamic simulations including the time-dependence of the microvascular resistances
Majid Harmouche, Amedeo Anselmi, Mahmoud Maasrani, Chiara Mariano,Herve Corbineau, Jean-Philippe Verhoye and Agnes Drochon

    This paper presents some simulations of fluxes and pressures in the coronary network, in the case of very severe coronary disease (several stenoses on the left branches and total occlusion of the right coronary artery). In that case, coronary artery bypass graft surgery is the commonly performed procedure. However, the success of the intervention depends on many factors. Modeling of the coronary circulation is thus important since it can help to understand the influence of all these factors on the coronary haemodynamics. We previously developed an analog electrical model that includes the eventual presence of collateral flows, and can describe the different revascularization strategies (two grafts, three grafts,
Key Words
    coronary three vessel disease; lumped parameter model; revascularization; flow profiles
Majid Harmouche, Amedeo Anselmi, Herve Corbineau, Jean-Philippe Verhoye: Department of Thoracic and Cardiovascular Surgery, Rennes University Hospital PontChaillou, Rennes, France

Majid Harmouche, Amedeo Anselmi, Herve Corbineau, Jean-Philippe Verhoye: Research Unit Inserm UMR 1099, LTSI, University Rennes1, Rennes, France

Mahmoud Maasrani: Faculty of Sciences, Lebanese University, Tripoli, Liban

Chiara Mariano: Politecnico di Torino, Torino, Italy

Agnes Drochon: University of Technology of Compiegne, UMR CNRS 7338, Compiegne, France

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