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Advances in Biomechanics & Applications
  Volume 1, Number 2, June 2014, pages 95-109
open access

Simulation of tissue differentiation around acetabular cups: the effects of implant-bone relative displacement and polar gap
Kaushik Mukherjee and Sanjay Gupta

    Peri-acetabular bone ingrowth plays a crucial role in long-term stability of press-fit acetabular cups. A poor bone ingrowth often results in increased cup migration, leading to aseptic loosening of the implant. The rate of peri-prosthetic bone formation is also affected by the polar gap that may be introduced during implantation. Applying a mechano-regulatory tissue differentiation algorithm on a two-dimensional plane strain microscale model, representing implant-bone interface, the objectives of the study are to gain an insight into the process of peri-prosthetic tissue differentiation and to investigate its relationship with implant-bone relative displacement and size of the polar gap. Implant-bone relative displacement was found to have a considerable influence on bone healing and peri-acetabular bone ingrowth. An increase in implant-bone relative displacement from 20
Key Words
    tissue differentiation; bone ingrowth; acetabular polar gap; bone healing; finite element analysis
Kaushik Mukherjee and Sanjay Gupta: Department of Mechanical Engineering, Indian Institute of Technology Kharagpur, Kharagpur 721302, West Bengal, India

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